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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425d60d18ff0ad8b82b7331ffc3090210c557b135dc3ec91c12fa48c56ade6c0' 
  AND token = 'IbY7ZDCP7KB8rgMdqJ1+24e4VbcK64elac6wk6vXSEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}