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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b450282150a4688916b5eed35d8c960bd5482b029e90057e5fadb61d8a49863' 
  AND token = '5fd6IIe2Xgd8Jx/DzD/swoos/CKbVmyd34mrQSHqTJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}