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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b68e22ee08034b17f40f9b48158ce7881d1191b9a9f3a8a2cb0ea9308a8740' 
  AND token = 'cR308j9lmTrf9b98LJMFlkJCNVq3jGn7PoSuBBjb0R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}