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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a6617cdee87e8f8d1c536b0d1014d2c03faa2418ea839aac846f2216e1700d' 
  AND token = 'ErOoIEPhEgoi7nK6gHEdrcdcZN0hUoMTMr+MKAbYugI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}