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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50f0af8d8a20428fb3bdd1ddc5a8d5a546b0cdf1f40783e213dc4f5dfcecf4e' 
  AND token = 'Iy1dz8qpRoDLOgdR52P5dwPHeQjnRKFzF4A+51cDxYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}