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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8de9a949882a120536e22c48f6394071d1707dec92841615cb8a1f5d15bf51' 
  AND token = 'Iw/XJ6fey++irOIQja0Q7TpN9LQLqC7aWFmwCbEpW/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}