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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f92c64b205adb8f1f9e2ac4e8721d50a1478018a855fea875835b6658ae5db' 
  AND token = 'esoZuQmy1rT2ECH0ytmyJOFVCCCJy+itmCxcbk5vimg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}