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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c03cd9b90b123572062ef1cdf8190b88425b7ee0d85cb12441698c678c4361' 
  AND token = 'APIbDSV/4LoSSj25efIIBCEKCySoJPGnI00evH3xY58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}