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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f8c0b917fb8fffa91fdd2701f067256f690016dc188fa1752b260abf1261ca5' 
  AND token = 'a6WYSxqUnPT8oSzyV3D8HC5Fwbc7UOUUfwLxSKuuyUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}