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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3161ef6822b37738289510ddf611106e96d90c26e3d477b63531ad0afc595bfb' 
  AND token = 'B4a9+gl7RE43j8qUMLIpuTzaAY4LSyTCJWb1nrtnioQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}