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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b836a278a647c3f56fd5346a271c051616d71ebf9f57d025de1c4e21f4518d' 
  AND token = '4fc0TV6nBSwH6GP+NGYH7jsK9XMxzx5RV8hrExfW1+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}