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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cd00b32cce4092a48b3e3316cc303cebf0551724b48d72185f3bb656c6e24a' 
  AND token = '4NwJcgEv/qPbUwgM3ADsNG8aaVPxeGS0TRFRMYm8co0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}