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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4159bcefa90bcf98cc1f863d0d45f8615e64232055d98c12c008baed7de71e58' 
  AND token = 'gLnfDuHcXgwB6CpGpJ60XyhjtWoxTTe3OJmY5utcN/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}