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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea7ed3c5ba19407f97a07b49c155eda66e8426045d28e90d470bc43793d008d' 
  AND token = 'y+Do9sv38tz9eUBBoWtrLckV0Zyem/n1UoyVGbhY7DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}