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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fc6d334952415732338e633ff6b330bd7f5c8542c4d1289867d868b5f9f3b4' 
  AND token = '88jw2SBJrghJxGL18zels5cVPzrxRM+RSfCJ596yso0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}