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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef65c6867cd5b9fabd56567363f82774ac412ca94a940713be33fe58be33614' 
  AND token = 'YKegMBr1suTRPiejHoMi6tfEOcBAF9gJ+KcN7G9pr0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}