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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ab4ec556f247bef40746319cecb4370ae875ec2361ab4dace440d0640eaedb5' 
  AND token = 'w0uaGaDADn9Hfe4RFDmgmCtCPyoxbBBKEALC8NK/rM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}