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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca7cd27d3031d9f2c2b3eb01f4009d63c23698772598aeeb26d86dd4ba358bd2' 
  AND token = 'H3pg4sL3t+hI52M9bznN4lT+52bvCrSsy8RxBmtmFP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}