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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c18a72f9b1a768659f68975289450898923be9ffd15e8458e22fd5565dc105' 
  AND token = 'RW7LqG61eYrwYId0J9JoFozKkVn9Xl6msbKPIPmLMss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}