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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed7d77afd6a4e1599acea938c278d08286b4cf67b27593b7e5e9a7f97d5ce53' 
  AND token = 'qEKLjSlvQCtt7u4vo1L7nCNn1z2U61KGCvOs6Rkjo00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}