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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddab6d67ecd08217be4f109a9655c20cf22d1f6a40be437041bb4fd7ca0872d1' 
  AND token = 'cefZij/MsoCCIdckc2bLUUT6ZgpShDm1PTBtueLU9yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}