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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c88ab5113d3e28cc4a464b1b5bde25056d16a8a71601d0cb0980b0eff189348c' 
  AND token = 'pci1Fm9+MDTwZnDmeol6RZpaV8NISe6REGzhQdC02eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}