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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '332ba37365a756b0c12cb28663e6692e03b022d13a80bcf2d9e79b1e8dc1f2cc' 
  AND token = 'r2pK6ObXGyAr40L/pzUIQ3A3W5CpvgQRnrtEutSQPdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}