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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd048b933c59af1695b4c86283c18cbf3b4321d22848cb6ee24c0c3d971c93201' 
  AND token = 'GgUg+deg9dLvQU3DdsxyenASMagxwWgVDOvdL0hcMds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}