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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5affe18056745c4b3e13f859fe5bf26b8cd934fbc09525149bb07ae97ac353' 
  AND token = 'EZOffeFHG4YfOp66okOSbmc/6cRyprr+ljoFM+CufWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}