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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '248bc1b823e6a4ed8821cfc09e3535138c6406c417bacd30d39d6dc2e2a386a7' 
  AND token = 'QLaa9da87GSaPuDzIzQ4JfvK5DAMXUZKdOPbEoL7U4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}