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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '329ce745aa84f661119f2263ed85b110bfc149c0b20b89e692d4495aeb237c7c' 
  AND token = 'afyfks0bAUnqi+dINJRefFuyi1eJR6IjuuJvCqSGQA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}