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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cb6bcbb60f44f6e7546c6725f22a9edf024a5ac326bf72f126db0f84f3b48a9' 
  AND token = 'kJoJdxgUPrE4pPx/FmLmgdjQTHQnWJS2cgOP3oOD4uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}