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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51390fac5c047b39e7aedf17d061f7af526d7c0d781de25e459acd735ee9965' 
  AND token = 'yp59FT9YcrciW0uoGO405AQszWu5bshyJNlw4yDOB/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}