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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c3a5be2b51c6fdf3213ee44e8d54bf968db9ba0527ed0e86caadd651fab750' 
  AND token = '00ZwNF11Vl+w7RESRGku89sEtoOr+tuSVZSS6peVqQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}