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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '775899e4943a7b6d4407e3cf22403ee3843312ef9f76c48c28d4d6305c995c29' 
  AND token = 'I62G7BffQo3M6RUhb/xFt6iNw9HXqjAIzr3Ujjb8VOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}