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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd468010587a05d00bce148c79fe8122809e6b87ef60c750be53b761776e61227' 
  AND token = 'HTQh+0qitwrZjj0mJfoIDc1DDG3gt/Uwqk7fgTGlnEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}