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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2e33c861e50b3ce572cd1ed99cbfc6114c0f07f670ee6358e2e19faefff0f7' 
  AND token = '+oW5cMuEfXSuofgCf0AZukkLo2AhsOPdlFQoN2zgXJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}