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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8021dd54b58ccaaf755ad9850d42fbf6a696257a434ac67b5c2381b84e965cd0' 
  AND token = 'Ttfwa+j3oEKKKancmq2ua8M0W7OX61UyL4mSgUtnBbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}