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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fe0a6f527475f7dfd152a3ff4848bce183352e2aac039db8c4ff0cebddacbe' 
  AND token = 'DPipQrrsSZZs93f9vNx1bHUla17/MOq5SA5+BHkgnb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}