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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91c153326bd00c465ebb4f8843b7ba431ec8b9bc3b6945e916f61468e36b70ff' 
  AND token = 'MOIGDp9bPj3wu1c0U3pPHY+3CB6IGGXiXLHh30CDpoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}