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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c418fea07b26e7b82c6d88ccf4d5a84ae57a47216d00f527ba7e606dc38f250c' 
  AND token = 'f+ALsQLgFxYQBqCZgoy7lK3Kvyb+f4knWPyHxl5HT3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}