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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5865f124dde174c9df7c9a7a8a990bc1eecdedfb9f85b4239f4ec40c8dadbfaf' 
  AND token = 'nzq5VDHdIAMKfRt4wUIF0Df+zpB+oqNXqsbMMf0jjL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}