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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c882a874fdc2a1d8d6cb866082c36c90c0b1cd47c02e4a1129ebb8ed735a39eb' 
  AND token = '1+I4DG7F4l21K7Fk1P+2f6ibv8xfCmQPeuTDuThI2MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}