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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f0e238040ea78cc67c2e764429186a7bb5fc20b11431ccfa108b675c1e5597' 
  AND token = 'K3v47Pp5OBfzHCs+P/6tMCLnvWpjPdBpyJDcRuETN2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}