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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b09f94d8d594a9dc68570b47ca9357b2181edbfe95227ef86bfefd00319f492' 
  AND token = 'r7t8AKfa9IheHm31L8SBSZEvr422fRWTId8YBM+bHEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}