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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27bf0e02aeec51b1c89eb71618f88ef45f0b61b6f49fb8959bfba12df510fa3' 
  AND token = '/2RhshllCipy7A7p6kYjmrhed1/2/yoh5iMaSGGgswA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}