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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd86ad580fd0c04488477eb148bb988ec77ebb90f89e1c869422d7450af01bae' 
  AND token = 'dCym4JX3ZRKdBf4UGROLXgrpVT/r93Zi6Li1++cTFEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}