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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '759ad72c02fc609816b89191dfdf24e0736cbdbcfb0aa7112c4e7ead4ed002a0' 
  AND token = '5wvJFNJzfQ+2MLboO/WmFCGFi6IFYGQG1J2yXYMQg7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}