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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fcfb7818277a39581b76b506a34bfbbcc4f3c4d6056b7381f3b485ecd5effb3' 
  AND token = 'mS6nVjkM0hw9KmQb6WjgK5TvQj07dSq1+K6Xe02i2EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}