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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54afa3b76ba96d5dd6ca408076336440bc60b3edbf22f451cbbfd2e82b7d2651' 
  AND token = 'nY+hCYmbId3cIak/mg7ltCN4e4Yk4u0FvEdt4LvLgo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}