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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61f9a8dca97964a18c7a9cb8759f3b0dec2943e00a980155f6214955e9b11427' 
  AND token = 'MincUJ5iQpEGr0zzbY1WJav/qpmJwbxf2YyaEeSVd+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}