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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ecfd7d894c47922537fb532e2c29f65e6f179e90f7e290a59f8bfb9bd443dc' 
  AND token = 'QPSQjPOmWojcfhU8Iw5zOUnaA9vi+SO9VprKc02ZlY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}