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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0521ef4968a0b91a46e0a0443cb63563b18d10bddd5f56e71e004d4da39a7a4e' 
  AND token = '5GyJ6qDPcY+xheex3/3DG4eHrQL4MIp5NCXSVK9Bhxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}