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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edbb1a15298b7b466dead192fc32c13987c8ab5365b9f25318ad67b22065f8d7' 
  AND token = 'fpvl6XFjYnTfnw1345EQgNHTnVplLKrxV7Bom2IiS78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}